mercury glutathione synthesis Methylmercury alters homeostasis by inhibiting glutaredoxin 1 and enhancing glutathione biosynthesis in cultured human astrocytoma cells One-carbon metabolism and glutathione (GSH)
Description
However, this feature of astrocytes to modify and thereby inactivate xenobiotics has also to be considered in the context of the application of therapeutic drugs for the treatment of neurological disorders, as GSHdependent removal of such compounds in astrocytes may lower the therapeutic benefit of a given treatment

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Pretorius E, Venter C, Laubscher GJ, Kotze MJ, Oladejo SO, Watson LR, et al

10.1007/s12035-016-0118-6 18 ChangL.AlicataD.ErnstT.VolkowN

The cells were further incubated with the anti-CD45-PerCP-Cy5.5 (1:100