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Interaction of G-protein betagamma complex with chromatin modulates GPCR-dependent gene regulation

The following clinical symptoms may be present when making the diagnosis: History of onset of the painful condition and its presumed cause (e.g., injury or sprain) Distribution pattern of pain consistent with the referral pattern of trigger points Range of motion restriction Muscular deconditioning in the affected area Focal tenderness of a trigger point Palpable taut band of muscle in which trigger point is located Local taut response to snapping palpation Reproduction of referred pain pattern upon stimulation of trigger point The goal is to treat the cause of the pain and not just the symptom of pain

Sucic et al., 2019