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6.3 Broad clinical potential of targeting ferroptosis in neurodegeneration Targeting ferroptosis offers a novel approach to neuroprotection by preserving cellular integrity, modulating inflammation, and enhancing antioxidant defenses
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10.1371/journal.pgen.1004228 218
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By anchoring to these positively charged side chains, CLR01 disrupts the electrostatic and hydrophobic contacts necessary for oligomer and fibril formation
