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Description
In reality, its effects develop slowly as the body adjusts and toxin levels decrease

J., Simpson K., Hume D

In the absence of myelin, redistribution of Na + occurs to maintain the transmission of nerve impulses that increases energy demand, and this produces a situation of virtual hypoxia. At the end, the demand exceeds the capacity of axonal mitochondria to produce enough ATP, which causes an increase in the concentration of Ca 2+ in the axon

It is commonly used in endocrinology research, molecular biology, receptor pharmacology, and peptide signaling studies

Protection of Normal Tissues from the Cytotoxic Effects of Chemotherapy and Radiation by Amifostine (WR-2721): Preclinical Aspects
