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Since macrophages tend to overlap when cultivated and the nuclei cannot be effectively seen, cell counting was performed using a haemocytometer only after the third exposure day

Many thiol-based ATs may lack tissue specificity, making it difficult to achieve therapeutic concentrations in the tissue/organ where the oxidative damage occurs (this phenomenon is also observed for other ATs discussed in this review)

hypothesize that the alanine 246 to threonine mutation in RF2 decreases the affinity for UAA

Dias C, Aires A, Bennett RN, Rosa EAS, Saavedra MJ

doi: 10.1182/blood.V92.7.2495 127 TakeiHArakiAWatanabeHIchinoseASendoF