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284 Research has also shown that depletion of riboflavin (vitamin B 2 ), which is essential for the formation of the FMN and FAD cofactors, leads to a general decrease in the levels of flavoproteins due to increased degradation of apoflavoproteins

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Combinatorial marker strategies for identifying and characterizing CSCs Given the limitations of individual CSC markers in terms of specificity and tumor type variability, recent efforts have shifted toward combinatorial marker strategies to increase the precision of CSC identification
