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For comparisons B and C, ORA was performed using the GOBP database 92 (release 2023) and the Reactome Pathway Knowledgebase 93 (release 2022) to identify over-represented pathways in the upregulated gene sets (padj 0.05 and padj 0.01, respectively)

(2) No confounders exist between genetic variation and the exposure-outcome association

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The buffer was prepared by mixing 19.6 g of sodium citrate tribasic dehydrate, 1 g of phenol and 16.5 mL of concentrated hydrochloric acid in water

Well-established safety when administered by professionals