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Effect of vitamin B12 supplement in metformin treated diabetic patients and its correlation to peripheral neuropathy

The historically important question, which has been the subject of frequent discussions, is whether oxidative stress is the primary cause or secondary consequence of the disease

Acute ethanol exposure in mice leads to decreased expression of GAD1, HDAC2, HDAC11 associated with decreased histone acetylation at GAD1, HDAC2 promoters and increased expression of MT1, MT2, EGR1 associated with increased levels of H3K4me3 at MT2 promoter and decreased level of H3K27me3 at the MT1 promoter in the cerebral cortex (Finegersh and Homanics, 2014a)

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