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however, Met expression was elevated in the radioresistant HNSCC models

The key distinction is that conventional treatments primarily target hormonal pathways (suppressing estrogen), while GLP-1 agonists target inflammatory and metabolic pathways

In fact, transplanting senescent cells into mice knee joint has been found to induce an osteoarthritis-like change (Xu et al., 2017)

This was seen in mice that were treated with 5 Amino 1 MQ, in which large-sized myofibers were observed as compared to the controls

EBioMedicine 61 , 103030 (2020)
