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The analogues, 1,8-diMQ and 5-amino-1MQ were tested at concentrations from 200 M 10 nM and 600 M 10 nM, respectively
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Oral capsules and liquids must fight their way through stomach acids and liver enzymes, resulting in a microscopic absorption rate of only 1% to 10%
Due to its shorter sequence, TB-500 offers enhanced metabolic stability and amenability to synthetic optimization compared to the parent protein
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