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Shi S, Lei S, Tang C, Wang K, Xia Z

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*Not recognized as an essential nutrient by the AAFCO Dog Food Nutrient Profiles

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Enhanced insulin action decreases the influx of free fatty acids to the liver and suppresses hepatic de novo lipogenesis

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The resulting acylcarnitine esters (e.g., acetylcarnitine) can remain in the mitochondrial matrix or be exported back into the cytosol via CACT

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Careful longitudinal clinical and imaging monitoring were recommended using MRI and FDG-PET to identify lesions of greatest concern to be biopsied

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