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Shi S, Lei S, Tang C, Wang K, Xia Z

*Not recognized as an essential nutrient by the AAFCO Dog Food Nutrient Profiles

Enhanced insulin action decreases the influx of free fatty acids to the liver and suppresses hepatic de novo lipogenesis

The resulting acylcarnitine esters (e.g., acetylcarnitine) can remain in the mitochondrial matrix or be exported back into the cytosol via CACT

Careful longitudinal clinical and imaging monitoring were recommended using MRI and FDG-PET to identify lesions of greatest concern to be biopsied
