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The following applies: Even though overdoses rarely have critical consequences, you should always use high doses with caution and have your blood levels checked regularly if you are unsure

But as we age, NAD+ levels naturally decline, leading to: Fatigue Brain fog Weight gain Poor sleep Decreased athletic performance Accelerated aging Thats where NAD+ therapy comes in

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Effect of colchicine and vinblastine on identified leech neurons
Jun 2013;56(2):382-8
