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) and peripheral lesions (e.g., cavernous nerve injury caused by pelvic surgery or pelvic fracture) ( 2 Neuropathology and animal models of cavernous nerve injury According to the Seddon classification, peripheral nerve injury is stratified into three degrees: neurapraxia, axonotmesis, and neurotmesis, whose severity increases in turn, as well as recovery time ( At present, the animal model of CNI takes rat as the main carrier, a recent consensus statement ( 3 Molecular pathogenesis of cavernous nerve injury-erectile dysfunction 3.1 Nitric oxide synthase/nitric oxide pathway Nitric oxide (NO), a key molecule in mediating penile erection, is catalyzed from L-arginine by nitric oxide synthase (NOS)

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