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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Michalczyk K., Ziman M

McCoy, J

Women with PCOS consistently show reduced follistatin expression in ovarian tissue, and this deficit appears to contribute to impaired follicle development and androgen accumulation within the follicular environment.[10] The therapeutic angle is intellectually compelling

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A related molecule with a 4'-oxo-butanoyl moiety in position sn -2 is an agonist for the platelet-activating factor receptor, while one with a 9-oxononanoyl or azelaoyl chain, generated from the oxidation of linoleic acid, triggers apoptosis by interacting with mitochondrial membranes and permeabilizing cytochrome C