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We recognize that the current study lacks external validation using an independent RNA sequencing cohort

Animal Model:NMRI-Hannover (male, 30 g, deep partial skin thickness burns induced by 5 s direct flame exposure covering 20% total body area) [2] Dosage:i.p.: 10 ng/kg, 10 g/kg

Pons R, Andreu AL, Checcarelli N, et al

Of note, similar to the situation in rats with inferior caval vein occlusion (Vukojevic et al., 2018), RTqPCR has the limitation of results only reflecting mRNA levels, which may not correlate with protein levels

These trials primarily investigate the antioxidant effect of glutathione in healthy individuals or various diseases