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These protocols have shown a cross-talk between neurons and endothelial cells, as well as control the diffusion of oxygen and nutrients

Drugs, 73(14), 1525-1547

10.1038/ncb3064 62 FuD.WangC.YuL.YuR

Highdose intravenous vitamin C combined with cytotoxic chemotherapy in patients with advanced cancer: a phase III clinical trial

For clinicians, distinguishing the root cause requires both patience and a nuanced touch: The 15-Second Rule: Confirming edema requires sustained digital pressure for 1015 seconds to check for "pitting" (a temporary, residual dent)
