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They found antibodies consisted of heavy and light protein chains, which joined together to form three sections yielding a molecule shaped like the letter Y (figure 19)

Researchers induced knee osteoarthritis in rabbits using collagenase injections, then treated the animals with weekly intra-articular injections of AOD-9604, hyaluronic acid, or a combination of both compounds

Structure of the molecule and their specificity towards enzymes is crucial to evaluate the stability of protein and peptide drugs (Bernkop-Schnurch, 1998)

doi: 10.1210/en.2012-2198

doi: 10.1016/j.pnpbp.2018.09.011 196 MondelliVBlackmanGKemptonMJPollakTAIyegbeCValmaggiaLRet al