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Abbreviations ARF: Acute renal failure BUN: Blood urea nitrogen CS: Chitosan EE %: Encapsulation efficiency percentage FTIR: Fourier Transform Infrared Spectroscopy GN: Gentamicin GSH: Glutathione IL-6: Interleukin-6 KIM-1: Kidney Injury Molecule-1 LS: Lepidium sativum MDA: Malondialdehyde NP: Nanoparticle NGAL: Neutrophil gelatinase-associated lipocalin PDI: Polydispersity index SCr: Serum creatinine SOD: Superoxide dismutase TEM: Transmission electron microscope TNF-: Tumor necrosis factor alpha References Jose, S

The pathway analysis module is the endpoint of the metabolomics study, where metabolites correlate to pathways indicating the biological response of the plant to the applied salinity stress