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Affiliation: Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA Email: [email protected] ORCID: Affiliation: Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA ORCID: Explor Dig Dis

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Hence, the system is not amenable to analysis in the same way as some pathways of carbon, nitrogen, and sulphur metabolism