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Description
Thus, inherited glutamine synthetase deficiency specifically affects the synthesis of NAD + from the NAD + precursors, tryptophan and nicotinic acid

Interestingly, this was also reflected in the protein abundance level of antioxidative enzymes

LC also aids in removing intermediate metabolites by binding them and transporting them outside the mitochondria for degradation [125]
[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Nakaya M, et al
Sci Rep 10 , 2200 (2020)
