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Molecular docking studies show that the 1,2,4oxadiazole 5(4 H )one portion binds to the active site of XO through hydrogen bonds, two of which are from the carbonyl group to the guanidine group of Arg880, and the other to the N4 atom which interacts with the hydroxyl group of Thr1010

Western blot analysis of GPX4 expression in HC neutrophils, monocytes, and lymphocytes (n = 7) cultured with 20% HC or SLE serum for 30 hours

For example, both ATF4 and XBP1s can activate ATF6 transcription, at least modestly

11:125910.3390/antiox11071259 Antioxidants 38 ImaiT.TsujiS.MatsubaraH.OhbaT.SugiyamaT.NakamuraS.et al (2021)

Int J Aging Res 2(1):117 Ayaz M, Sadiq A, Junaid M, Ullah F, Ovais M, Ullah I, Ahmed J, Shahid M (2019) Flavonoids as prospective neuroprotectants and their therapeutic propensity in ageing-associated neurological disorders